Biological
Efficacy

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Targeted in vivo studies to advance your therapeutics

We provide science-driven, custom solutions to evaluate the therapeutic potential of your molecules including monoclonal or bispecific antibodies, ADCs, small molecules using preclinical mouse models.

Our tailored proof-of-concept platforms support confident decision-making at every stage of oncology and other therapeutic areas.

Custom Study Design

Tailored in vivo studies aligned with your research goals.

High
Reproducibility

Expert staff, robust and innovative tools, ensure reliable and consistent data.

Predictive & Translational Models

Validated models linking preclinical data to therapeutic impact.

European Production

To support researchers, biotechs, startups and pharmas with tailored solutions.

From micrograms to grams

We deliver the quantity you need for your projects.

Custom Quotes or Integrated Project Solutions

Our comprehensive quality checks guarantee that every batch matches your exact needs.

Quality assurance

ISO 9001 certification guarantees the quality of our services.

Choosing the appropriate pre-clinical model is key to generate meaningful, translatable results. Our experts combine in-depth scientific expertise with proven operational excellence to guide the selection of in vivo models that best serve your objectives. We offer a comprehensive portfolio of established and innovative models to assess efficacy and mechanisms of action across oncology, inflammation and infectious diseases.
Our pre-clinical platform provides a comprehensive evaluation of the therapeutic potential of your molecules by integrating tumor growth inhibition, survival and animal health metrics in physiologically relevant models. This holistic approach anables smarter dose selection and accelerates progression toward advanced models and clinical development. We provide standardized protocols with flexible customization and the capacity to support large scale studies.
PK/PD studies provide essential data to understand the behavior of your drug in vivo. We deliver critical insights on drug exposure, distribution, and pharmacologic effect that helping you optimize dosing and accelerate decision-making. We also generate robust data to support regulatory submission. Key benefits:
  • Define optimal dose & schedule early
  • Predict efficacy through dose–response modelling.
Ensure safe and effective drug development with our comprehensive in vivo safety and toxicity evaluations. We offer Maximum Tolerated Dose (MTD) studies in relevant animal models to identify dose-limiting toxicities and define exposure limits prior to efficacy or regulatory studies. Clinical observations, hematology and histopathology analyses are performed across a wide range of samples including blood, plasma and tissues. Key benefits:
  • Acute toxicity studies to rapidly detect adverse effects
  • Optimize dosing for subsequent efficacy studies
  • Reduced risk for comprehensive toxicological profiling.

Tumor models

Tumor cells can be implanted in various mouse models, from wild-type to genetically modified strains, including, knock-in, knock-out, and humanized models. Mouse strain selection is guided by tumor cell type and study objectives to ensure translational relevance and robust pre-clinical insights. Additional custom models can be developed upon request.

Immune cell profiling

Understanding which immune cells drive diseases such as cancer is key for advancing immunotherapies. We offer up to 30 standardized panels, each customizable with your biomarker of interest, enabling broad immune profiling or targeted specific cell populations analysis. We offer analysis in blood, tumors and lymphoid tissues with the capacity to process large sample volumes.

Additional service to go further

Complement your in vivo studies with advanced analyses and integrated support to accelerate decision-making and de-risk your development pipeline. We offer multi-parametric analyses, including cytokine assays, and pathway activation studies (Characterization Assays) to strengthen your data.

Accelerate Drug Development with Relevant In Vivo Models

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